- Zulte Waregem v Wigan Athletic 6:00pm
- Real Betis v Lyon 8:05pm
Matchday 2 : Thursday October 3
- Sevilla v SC Freiburg 6:00pm
- Wigan Athletic v Maribor 8:05pm
Matchday 3 : Thursday October 24
- Real Betis v Vitoria Guimaraes 6:00pm
- Wigan Athletic v Rubin Kazan 8:05pm
Matchday 4 : Thursday November 7
- Rubin Kazan v Wigan Athletic 5:00pm
- Maribor v Zulte Waregem 6:00pm
- Sevilla v Slovan Liberec 8:05pm
- Lazio v Apollon 8:05pm
Matchday 5 : Thursday November 28
- Lyon v Real Betis 6:00pm
- Wigan v SV Zulte Waregem 8:05pm
Matchday 6 : Thursday December 12
- Wigan Athletic v Zulte Waregem 8:05pm
Round of 32 : Thursday February 20
- Juventus v Trabzonspor 6:00pm
- Dynamo Kiev v Valencia 6:00pm
- FC Porto v Eintracht Frankfurt 8:05pm
- Ajax v Salzburg 8:05pm
Round of 16 : Thursday March 13
- Ludogorets v Valencia 6:00pm
- Juventus v Fiorentina 8:05pm
Quarter-finals : Thursday April 10
- Valencia v FC Basel 8:05pm
- Benfica v AZ Alkmaar 8:05pm
